Table 2.
DPB1 allele frequency in childhood leukaemia in relation to karyotype
| DPB1* allele | Frequency (f ×100)b | ||||
|---|---|---|---|---|---|
| Supertypea | TEL-AML1 | HeH | OTHER | CONTROL | |
| 0101 | GKD | 2.55 | 3.92 | 6.04 | 7.99 |
| 0201 | GEG | 9.69 | 9.97 | 9.58 | 5.96 |
| 0202 | GEG | 1.53 | 0.82 | 1.05 | 0.64 |
| 0301 | LKD | 10.71 | 9.48 | 10.50 | 11.46 |
| 0401 | GKG | 44.39 | 47.06 | 46.46 | 45.25 |
| 0402 | GKG | 12.76 | 13.07 | 12.07 | 11.52 |
| 0501 | GKD | 2.04 | 1.47 | 1.97 | 3.01 |
| 0601 | LED | 3.06 | 1.63 | 2.49 | 0.35 |
| 0801 | GED | 0.33 | 0.26 | 0.06 | |
| 0901 | LED | 1.02 | 0.98 | 0.52 | 1.10 |
| 1001 | LED | 1.53 | 2.78 | 1.44 | 1.45 |
| 1101 | [LRD] | 3.57 | 2.29 | 1.31 | 3.76 |
| 1301 | LED | 0.51 | 1.63 | 2.23 | 1.74 |
| 1401 | LKD | 2.55 | 0.49 | 0.39 | 0.81 |
| 1501 | [GRV] | 0.51 | 0.98 | 0.79 | 0.81 |
| 1601 | GED | 1.02 | 0.06 | ||
| 1701 | LED | 1.14 | 0.92 | 0.23 | |
| 1801 | [GKV] | 0.41 | |||
| 1901 | GED | 1.53 | 1.14 | 0.66 | 0.35 |
| 2001 | LKD | 0.16 | 0.13 | 0.06 | |
| 2101 | LED | 0.17 | |||
| 2301 | GKG | 0.26 | 0.46 | ||
| 2401 | GKG | 0.13 | |||
| 2501 | LKD | 0.51 | 0.13 | ||
| 2601 | LKD | 0.16 | 0.13 | 0.58 | |
| 2701 | LKD | 0.51 | 0.23 | ||
| 3001 | LED | 0.13 | 0.06 | ||
| 3301 | GEG | 0.13 | |||
| 3401 | [GKV] | 0.17 | |||
| 3501 | LKD | 0.16 | 0.13 | ||
| 3601 | LED | 0.06 | |||
| 3901 | GKG | 0.64 | |||
| 4401 | LED | 0.06 | |||
| 4801 | GEG | 0.17 | |||
| 4901 | GKG | 0.16 | |||
| 5001 | GKD | 0.06 | |||
| 5101 | GKG | 0.16 | |||
| N | 95 | 300 | 381 | 864 | |
aSupertypes designated by polymorphic amino acid residue (aa) in the P6, P4 and P1 peptide binding pockets (PBP). Single letter amino acid (aa) codes are used throughout: G, glycine; E, glutamic acid; K, lysine; D, aspartic acid; V, valine; R, arginine; L, leucine. Supertypes in parentheses are not analysed further
bDPB1 allele frequencies (f x 100) calculated using POPGENE (see “Materials and methods”)