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General mechanisms of modifying chromatin
| Transcription factors and cofactors target chromatin modifiers to specific genes |
| MicroRNAs target chromatin modifications to specific genes or groups of genes to mediate transcriptional gene silencing |
| Variant histone exchange |
| Direct phosphorylation of histones via MAPK activated kinases |
| Nucleosome remodeling complexes (SWI/SNF, etc.) slide or displace nucleosomes |
| Global chromatin modifications, e.g., charge effects |
| Histone code |
