Fig. 3.

Activated R-Ras increased metastatic potential of cervical epithelial cells. Livers of female Fox Chase C.B-17-scid mice 42 days after i.v. injection of 10 × 10⁶ C33A cells transfected with a R-Ras87L, b PI 3-K p110, c R-Ras43N, or d empty vector. e Number of metastatic foci at the liver surface. Data shown are the mean ± standard error values from three animals for each cell type. Differences were statistically significant (*) at P ≤ 0.003 in ANOVA test