Fig. 3.
Tumor-conditioned medium diminishes CD34+ cell development into CD205+ dendritic cells through a VEGF-independent pathway. CD34+ cells were seeded under conditions to support myeloid cell growth in the presence or absence of 40% tumor-conditioned medium. After 7 days, they were detached and immunostained for CD205. Shown in the top panels are representative histograms from five similarly conducted studies. In the panel below is a summary of the mean percentages of CD205 cells ± SEM from five different analyses