Table 4.
Cytokine gene expression ratios in relation to normal tissue in pancreatic carcinoma specimens
| Gene expression ratioamedian (range, min-max) | P valueb | |
|---|---|---|
| IL-1β | 28.5 (2.3–237.9) | <0.001 |
| IL-2 | 1.9 (0.14–54) | 0.2 |
| IL-6 | 62.4 (0.8–2313.9) | <0.001 |
| IL-8 | 213.4 (2.8–810.8) | <0.001 |
| IL-10 | 56.5 (0.3–208.3) | <0.001 |
| IL-11 | 54.6 (0.7–635.5) | <0.001 |
| IL-12 p40 | 3.7 (0.4–29.5) | 0.01 |
| IL-13 | 0.03 (0.006–0.98) | <0.001 |
| IL-18 | 12.9 (3.9–28.4) | <0.001 |
| IFN-γ | 5.6 (0.22–85.6) | 0.004 |
| TGF-β1 | 474.4 (44.9–2907.1) | <0.001 |
| TGF-β2 | 83 (8.6–260.4) | <0.001 |
| TGF-β3 | 173.9 (18.2.1–2171.6) | <0.001 |
aCalculated according to the REST-software, bMann–Whitney test