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Chimeric virus replication
| Virus | Replication in PHA-stimulated PBL (p24, ng/ml) at day postinfectiona:
|
||
|---|---|---|---|
| 3 | 5 | 8 | |
| SF162 | 3.4 | 12.3 | 18.5 |
| HXB2 | 0.4 | 4.6 | 8.9 |
| HXB2.SF162 | 1.2 | 9.3 | 12.3 |
| HXB2.605.24 | 0.3 | 1.2 | 3.0 |
| HXB2.612.30 | 0.4 | 2.0 | 5.2 |
| HXB2.612.31 | 0.4 | 2.8 | 6.1 |
Transfected HEK cell supernatants were normalized for p24 antigen levels (1.5 ng) and used to infect 3-day-old PHA- and IL-2-activated PBL. Extracellular fluid was harvested at 3, 5, and 8 days postinfection and assayed for p24 antigen.
