Fig. 3.

The effect of intravenous administration of muS110 on leukocyte numbers. Female C57BL/6 mice (n = 30) received intravenous injection of 15 μg/kg muS110 or control BiTE antibody. a Hematokrit, b total numbers of leukocytes, c T cells, and d B cells were determined before and 2, 4, 8, 24 h after BiTE antibody administration (n = 5) using antibodies directed against murine CD45, CD3, and CD19 with TruCOUNT Tubes (BD Bioscience, Heidelberg, Germany). Error bars indicate standard error of the mean