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. Author manuscript; available in PMC: 2025 Apr 1.
Published in final edited form as: Lab Invest. 2024 Jan 28;104(4):102025. doi: 10.1016/j.labinv.2024.102025

Figure 4. IOP changes in GDF15 null mice.

Figure 4.

A). To determine the effects of absence of GDF15 expression on IOP, IOP was evaluated in GDF15 null mice (10-month-old) using a rebound tonometer. GDF15 null mice (KO; n=16 eyes) showed no change in IOP compared to the age-matched wild type mice (n=20 eyes). B). Light microscopy based histological examination showed no recordable differences in the conventional AH pathway, and in ciliary body (CB)) between GDF15 null and wild-type mice. TM; trabecular meshwork, SC; Schlemm’s canal, KO; knockout, WT; wild type, ns; not significant. Bar indicates image magnification.