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. Author manuscript; available in PMC: 2025 Feb 1.
Published in final edited form as: Sleep Health. 2023 Dec 11;10(1 Suppl):S41–S51. doi: 10.1016/j.sleh.2023.10.005

Table 1:

Characteristics of the proteins in Figure 3.

* C for Circadian, R for Rhythmic 1-harmonic model 2-harmonic model
Seq-id Name Gene UniProt Class* p-rhy p-com A φ p-rhy p-com A1 A2 φ1 φ2
23326–10 Glutathione S-transferase A2 GSTA2 P09210 C 3.76E-05 1.22E-01 0.223 7.7 2.24E-08 3.20E-04 0.230 0.070 7.5 18.7
9204–33 Pro-opiomelanocortin POMC P01189 C 9.12E-42 2.06E-01 0.175 11.3 5.44E-44 2.19E-01 0.176 0.060 11.2 16.2
7921–65 Four-jointed box protein 1 FJX1 Q86VR8 C 6.24E-47 4.51E-01 0.164 3.5 8.28E-49 3.27E-01 0.166 0.047 3.5 12.0
3509–1 C-C motif chemokine 15 CCL15 Q16663 C 2.20E-17 5.84E-01 0.132 5.0 1.79E-15 5.85E-01 0.133 0.020 5.0 15.9
8620–56 Kallikrein-14 KLK14 Q9P0G3 C 5.75E-09 5.54E-02 0.100 7.6 2.84E-09 1.09E-02 0.100 0.023 7.7 15.1
5954–62 Parathyroid hormone PTH P01270 C 5.75E-05 1.13E-01 0.075 2.1 2.44E-06 4.16E-02 0.078 0.045 2.0 10.0
24490–16 THAP domain containing protein 4 THAP4 Q8WY91 C 7.34E-08 1.97E-02 0.096 8.8 2.39E-06 5.48E-02 0.098 0.022 8.9 19.2
2212–69 Tissue-type plasminogen activator PLAT P00750 C 4.63E-11 1.88E-01 0.165 10.7 6.65E-11 2.63E-02 0.160 0.005 10.7 13.8
10574–10 Beta-2-microglobulin B2M P61769 C 5.96E-05 7.92E-01 0.088 7.0 5.25E-04 7.50E-01 0.089 0.023 6.9 13.2
24957–6 Espin None B1AK53 C 4.39E-08 2.47E-01 0.086 6.5 9.92E-09 1.28E-01 0.086 0.033 6.3 11.8
18289–16 C-C motif chemokine 15 CCL15 Q16663 C 3.38E-21 2.88E-01 0.101 5.2 7.58E-19 2.03E-01 0.101 0.007 5.3 16.8
25048–30 Protein kinase C and casein kinase substrate in neurons protein 2 PACSIN2 Q9UNF0 C 1.45E-04 1.29E-01 0.194 21.1 4.05E-05 2.83E-02 0.197 0.075 21.2 4.8
21495–134 Prosaposin receptor GPR37 GPR37 O15354 C 1.51E-15 6.85E-02 0.086 4.8 7.46E-16 6.52E-03 0.087 0.014 4.7 13.8
9264–11 Cathepsin O CTSO P43234 C 9.87E-10 6.31E-02 0.075 13.9 5.13E-08 8.64E-02 0.078 0.003 13.9 0.6
15686–49 Inhibin beta C chain INHBC P55103 C 5.70E-10 4.21E-01 0.087 18.5 8.82E-09 2.35E-01 0.087 0.011 18.4 8.8
15375–49 Carboxypeptidase B CPB1 P15086 C 3.80E-05 1.13E-01 0.073 21.8 2.15E-04 1.20E-01 0.079 0.022 21.7 4.8
5668–49 Anterior gradient protein 3 AGR3 Q8TD06 R 4.22E-02 1.45E-01 0.032 23.4 1.34E-05 6.52E-03 0.035 0.044 23.3 10.1
17342–13 Anterior gradient protein 3 AGR3 Q8TD06 R 2.97E-02 2.38E-01 0.086 23.5 1.08E-05 9.84E-03 0.090 0.098 23.5 11.3
13118–5 SPARC-related modular calcium-binding protein 1 SMOC1 Q9H4F8 R 2.43E-14 4.27E-12 0.026 19.9 1.82E-17 1.92E-12 0.026 0.031 19.9 10.2
9384–17 Cathelicidin antimicrobial peptide CAMP P49913 C 4.90E-01 3.45E-01 0.008 14.9 4.57E-04 1.46E-01 0.010 0.032 14.3 21.9

Notes: The provided values for amplitudes and acrophases represent the average results across the four conditions employed in the analysis. Seq-Id is a unique id used by SomaLogic to measure proteins. UniProt provides a unique reference to a protein in UniProt database. In column class, “C” stands for Circadian while “R” stands for for Rhythmic. P-rhy is the adjusted p-value that tests if there is a rhythm. P-com is the adjusted p-value that tests if rhythms are different. The first block of proteins corresponds to the proteins in Figure 3 B while the last block corresponds to Figure 3 A. The middle block provides additional circadian proteins.