Table 1:

Consensus Broders grading system

Grade	Presence of keratin pearls	Tumor cells	Mitotic figures
Grade 1 (well-differentiated)	Numerous	Mature, with abundant eosinophilic cytoplasm, intercellular bridges and large but uniform nuclei	<3 mitotic figures per 10 HPF
Grade 2 (moderately differentiated)	Rare	Pleomorphic nuclei (even focally), with less abundant cytoplasm, indistinct intercellular bridges	3–10 mitotic figures per 10 HPF
Grade 3 (poorly differentiated)	Very rare/Absent	Hyperchromatic and very pleomorphic nuclei, scant cytoplasm	>10 mitotic figures per 10 HPF

HPF, high-power fields