Fig. 2. Male SMA body weights are higher at younger ages, but decay with a rate comparable to female pups.

a) Body weight progression curves of SMA pups SMA weights, as well as control pups. b) Body weight progression curves of just SMA pups with a smaller y-axis range to emphasize relative differences. Individual data points are plotted, and significant differences are shown. Multiple unpaired Student’s t-tests with Welch correction. c) Linear regression of the average body weights from P8 (peak body weight) to P16, to indicate the linear decrease in body weight over time between male and female SMA pups. Lines of best fit and their slopes are shown for both male (blue) and female (red). *p < 0.05, **p < 0.01; linear regression analysis, comparison of line of best fits. All sample sizes (n) are shown in Table 1.