Table 1. Five compounds prioritized by the toxicity filtering pipeline.

LD99.99 is calculated by fitting a four-parameter dose-response curve to the CFU/mL vs compound concentrations graphs in the presence or absence of 0.55 mM BSA, extracting the Hill slope and IC₅₀, and solving for the concentration needed to reduce the bacterial load by 4 log CFU/mL. Tanimoto similarity to most similar known antibiotic is computed with RDKit fingerprints.