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. Author manuscript; available in PMC: 2025 May 1.
Published in final edited form as: Am J Ophthalmol. 2024 Feb 3;261:141–164. doi: 10.1016/j.ajo.2024.01.023

Figure 4. OCT exposed neural canal (ENC) region anatomy and segmentation in representative Non-Highly Myopic and Highly Myopic Eyes.

Figure 4.

(A1-F1) OCT prelaminar neural canal anatomy. (A2-F2) OCT B-scans from the locations denoted by a green line in panels A1-F1. (A3-F3) OCT ENC region anatomic landmarks. (A4-F4) Pertinent ENC region and EOCBT and ESF sub-region segmentations. We define an EOCBT region to be internal to BMO extending to the ASCO which defines the CBT insertion into the scleral flange. We define an ESF region to extend from the ASCO to the SFO and to be devoid of overlying choroid and/or Bruch’s membrane. (A1-A4) Study eye FDA124 does not demonstrate an ENC region because the CBTs are internally oblique in all ONH segments. ((A1)-(C4)) Panels A - C show three non-highly myopic eyes with their increasing ENC regions by radial and sectoral extent. The ENC region of each eye contains both EOCBT and ESF sub-regions. ((D1)-(F4)) Panel D - F show three highly myopic eyes with their increasing ENC regions by radial and sectoral extent, in which the ESF and/or EOCBT region is even further elongated. All eyes are shown in right eye orientation.