Table 4.
Demographic and Ocular Characteristics of the Study Participants for the Highly Myopic Healthy (Hi-Myo-Healthy) and Highly Myopic Glaucomatous (Hi-Myo-GL) Eyes.
| Hi-Myo Eyes (n=122) | ||||||
|---|---|---|---|---|---|---|
|
| ||||||
| Hi-Myo-Healthy Eyes (n=64) | Hi-Myo-GL Eyes (n=58) | |||||
|
| ||||||
| All Eyes (n=64) | Non-Hi-ESF Eyes (n=17) | Hi-ESF Eyes (n=47) | All Eyes (n=58) | Non-Hi-ESF Eyes (n=18) | Hi-ESF Eyes (n=40) | |
| Female Gender (n (%)) | 34 (53.1) | 7 (41.2) | 27 (57.5) | 24 (43.4) | 10 (55.6) | 14 (35.0) |
| Left Eye (n (%)) | 34 (53.1) | 7 (41.2) | 27 (57.5) | 24 (43.4) | 10 (55.6) | 14 (35.0) |
| Age (year ± SD, (range)) | 50.9 ± 13.6 (26.0 to 79.2) | 44.2 ± 12.5 (26.0 to 65.7) | 53.3 ± 13.3 (27.0 to 79.2) | 67.2 ± 11.5*** (41.3 to 87.8) | 68.7 ± 11.5*** (50.0 to 84.1) | 66.5 ± 11.5*** (41.3 to 87.8) |
| Axial Length (mm ± SD, (range)) | 26.76 ± 0.90 (24.84 to 29.69) | 26.70 ± 0.97 (24.84 to 28.14) | 26.78 ± 0.89 (25.12 to 29.69) | 27.22 ± 1.05 (24.86 to 30.74) | 27.22 ± 1.06 (26.16 to 29.74) | 27.22 ± 1.07 (24.86 to 30.74) |
| Spherical Equivalent (diopter ± SD, (range)) | −7.04 ± 2.32 (−12.75 to 0.00) | −7.49 ± 1.54 (−11.00 to 6.13) | −6.87 ± 2.54 (−12.75 to 0.00) | −4.67 ± 2.78*** (−8.38 to 0.75) | −4.99 ± 2.51** (−7.50 to −0.38) | −4.52 ± 2.91*** (−8.38 to 0.75) |
| IOP (mmHg ± SD, (range)) | 16.0 ± 3.6 (8.5 to 26.0) | 15.4 ± 3.9 (8.5 to 24.0) | 16.3 ± 3.4 (10.0 to 26.0) | 14.3 ± 4.6 (2.0 to 32.0) | 13.6 ± 3.4 (7.0 to 20.0) | 14.5 ± 5.1 (2.0 to 32.0) |
| CCT (μm ± SD, (range)) | 549.8 ± 39.2 (457.0 to 629.3) | 529.6 ± 35.4 (457.0 to 602.7) | 556.9 ± 38.4 (475.0 to 629.3) | 537.2 ± 42.6 (425.3 to 617.3) | 535.5 ± 45.2 (449.0 to 617.3) | 537.9 ± 42.1 (425.3 to 607.0) |
| Mean deviation (dB ± SD, (range)) | −1.00 ± 1.52 (−5.43 to 1.86) | −1.00 ± 1.65 (−4.21 to 1.86) | −1.00 ± 1.49 (−5.43 to 1.61) | −9.19 ± 6.08*** (−23.27 to −0.46) | −7.12 ± 4.99*** (−16.98 to 0.46) | −10.13 ± 6.35*** (−23.27 to −0.63) |
Data for each group are reported for “All Eyes” as well as for “Hi-ESF and for “Non-Hi-ESF” sub-groups (Hi-ESF eyes were defined to be those eyes in which the magnitude of the ESF subregion was ≥ 100 μm in at least one ONH sector – (see Methods). Within the Hi-Myo eyes (Right Panel), data in bold red with asterisks are significantly different from the Non-Hi-Myo value (Left Panel) for the same sub-group and remain significant using a Holm-Bonferonni correction for multiple comparisons
(p < 0.001
p < 0.01
p < 0.05, t test or Chi-square test). Within the Hi-ESF column of both groups, obelisks denote data that are significantly different from the Non-Hi-ESF eyes of the same group and remain significant using a Holm-Bonferonni correction for multiple comparisons
p < 0.001
p < 0.01
p < 0.05, (t test or Chi-square test)).