Table 2:

Quality of Life and Illness Impact Measures by Pain (K=3) and Urgency (K=2) Clusters

	Pain Cluster					Urgency Cluster
QoL and Illness Impact	Cluster 1	Cluster 2	Cluster 3	p-value	Adjusted p- value*	Cluster 1	Cluster 2	p-value	Adjusted p- value**
SYM-Q7 Mood (0-10 @ 6 mos.	2.05	3.82	4.40	0.0002	0.0044	3.68	4.20	0.13	0.29
Perceived Stress Score (PSS) @ 6 mos	13.24	16.38	17.26	0.0581	0.3478	16.16	16.86	0.54	0.97
PROMIS Sleep @ 6 mos.	49.72	53.24	56.44	0.0009	0.0436	53.70	55.37	0.22	0.91
PROMIS Fatigue @ 6 mos.	49.22	54.84	56.82	0.0027	0.0926	54.96	55.64	0.63	0.45
HADS Depression (0-21) @ 6 mos.	3.43	5.76	6.08	0.0415	0.4587	5.54	5.83	0.65	0.67
HADS Anxiety (0-21) @ 6 mos.	5.30	6.84	8.37	0.0021	0.0222	6.76	8.13	0.042	0.12
CSQ Sum @ 6 mos.	5.66	9.50	11.47	0.0031	0.0605	9.55	10.70	0.33	0.54

^*Adjustment for baseline pain (PPS, 6 months)

^**Adjustment for baseline urinary urgency (USS, 6 months)