Extended Data Table 5.

Comparison of adjusted estimates from multiple imputed data using the MICE models, with estimates from complete case analysis for the improvement from depressive symptomatology (PHQ-9 scores < 10) at 5 months, and for a reduction in PHQ-9 scores by at least 50% between baseline and 3 and 5 months (secondary outcome)

MICE, multiple imputation by chained equations; OR, odds ratio; PHQ-9, 9-item Patient Health Questionnaire

^aThe secondary outcome of improvement from depressive symptomatology was defined as PHQ-9 scores less than ten.

^bThe secondary outcome of reduction in depressive symptomatology was defined as PHQ-9 scores reducing by at least 50% between baseline and the first and second follow-up assessments (yes/no).

^cOdds ratios and 95% CIs were calculated using logistic regression models adjusted for sex, age group and baseline severity of PHQ-9 (categorical).

^dAll estimates had missing data imputed by trial arm using MICE models that included sex, age group, baseline severity of PHQ-9 (categorical) and predictors of missingness.

^eAll P values reported are based on two-sided Wald tests from the relevant logistic regression model, with no adjustments for multiple tests.