Table 2.
FVPs, averted cholera cases, OCV campaign efficiency and percent of true cases averted across different modeling scenarios, 2022–2035
| Threshold | Fully vaccinated population (million) | Averted cases (million) | OCV efficiency (averted cases per 1,000 FVPs) | Percent of true cases averted | ||||
|---|---|---|---|---|---|---|---|---|
| Clinical definition | Decentralized testing | Clinical definition | Decentralized testing | Clinical definition | Decentralized testing | Clinical definition | Decentralized testing | |
| 1/10,000 per year | 391.8 (378.8–412.2) | 274.6 (261.1–285.8) | 0.76 (0.69–0.84) | 0.71 (0.64–0.8) | 1.9 (1.7–2.2) | 2.6 (2.4–2.9) | 44.7 (44.3–45.3) | 41.8 (41–42.9) |
| 2/10,000 per year | 275.2 (264.5–283.9) | 165.2 (153.9–179.4) | 0.7 (0.64–0.79) | 0.62 (0.55–0.71) | 2.6 (2.3–2.8) | 3.7 (3.4–4.2) | 41.5 (40.8–42.7) | 36.5 (35.4–38.1) |
| 10/10,000 per year | 65.2 (59.8–71) | 30.1 (24.4–37.9) | 0.45 (0.38–0.53) | 0.33 (0.26–0.41) | 6.9 (6–7.8) | 10.8 (9.4–12.6) | 26.5 (24.4–28.5) | 19.2 (16.7–22.3) |
For combinations of modeling scenarios that vary by incidence rate threshold and bacteriological confirmation capacity, we report the median estimates and 95% PIs in parentheses for FVP, true averted cases (millions), true averted cases per 1,000 FVPs (OCV efficiency) and percentage of true cases averted. ‘Clinical definition’ refers to a scenario without testing of suspected cases, while ‘decentralized testing’ refers to a scenario with systematic testing of suspected cases with RDT and culture in district-level laboratories.