Table 1.

Summary of Clinical Courses

Patient #	Eosinophilia Diagnosis	Presentation						Follow-Up
		Symptoms/Diagnosis	Imaging	Active Inflammation	Histology	Steroid Treatment	Other Therapies	Imaging	Steroid Dependence	Cardiac-Related Readmissions
1	HES	Transient amnesia, CVA, moderate pericardial effusion with early tamponade	TTE LVEF 35%-40%; CMR LVEF 31%	Yes	Eosinophils on myocardial, bone marrow, and pleural fluid samples	60 mg prednisone followed by taper	300 mg mepolizumab monthly	TTE LVEF At rest 45%-50%, stress 60%-65%	No	0
2	EGPA	Chest pain, myopericarditis	CMR LVEF 50%	Yes	None	None	Colchicine, 300 mg mepolizumab monthly	TTE LVEF 50%-55%	No	0
3	HES	Basal ganglia IPH	TTE LVEF 45%-50%	Unknown	None	40 mg prednisone daily for 14 days then every other day	300 mg mepolizumab monthly	TTE LVEF 40%-45%	Yes, at reduced dose	0

CMR = cardiac magnetic resonance imaging; CVA = cerebrovascular accident; EGPA = eosinophilic granulomatosis with polyangiitis; LVEF = left ventricular ejection fraction; HES = hypereosinophilic syndrome; IPH = intraparenchymal hemorrhage; TTE = transthoracic echocardiography.