FIG. 3.

Amino acid sequence alignment of an RT fragment from sequential samples of two HIV-1 group O-infected individuals. A fragment of 192 amino acids (spanning codons 28 to 219) from two sets of longitudinal samples (ESP1 and ESP2) is shown. The top line is the consensus amino acid sequence from the first group O pol sequence described in Spain (ESP1/0) (50) and corresponds with time zero for the longitudinal samples. Symbols are described in the legend to Fig. 2. Those residues involved in resistance to RT inhibitors (16) for which amino acid substitutions were found are numbered. Boxes enclose the sequences from longitudinal samples.