Table 2.
Comparison of brain volume and hemisphere-specific cortical volume, surface area, and GI between twins with higher and lower TTP with statistical findings.
| Measure | Mean (SD) | P, higher versus lower TTPa | |||
|---|---|---|---|---|---|
| Higher TTP | Lower TTP | Unadjusted | Adj FGR | Adj FGR and body volume | |
| Brain volume, mm3 | 263,043 (54,603) | 288,261 (68,322) | 0.009 | 0.049 | 0.57 |
| Cortical volume, mm3 | |||||
| Left | 21,990 (7,180) | 23,439 (8,019) | 0.0001 | 0.035 | 0.50 |
| Right | 21,998 (8,094) | 24,078 (8,219) | |||
| Surface area, mm2 | |||||
| Left | 10,474 (2,363) | 11,117 (2,607) | <0.0001 | <0.0001 | 0.002 |
| Right | 10,562 (2,500) | 11,101 (2,614) | |||
| Gyrification index | |||||
| Left | 1.139 (0.058) | 1.142 (0.059) | 0.63 | 0.14 | — |
| Right | 1.142 (0.062) | 1.139 (0.061) | |||
aMain-effect comparison in linear mixed model, including random effect for twin pairs. TTP × hemisphere interaction was nonsignificant in all cases.