Table 1.
BA.1 RBD-reactive scFv clones and their BCR-HC clonotypes
| scFv clone | scFv library (vaccinees) | HCDR3 sequences | IGHV | IGHJ | No. of vaccinees with the corresponding BCR HC clonotype |
|---|---|---|---|---|---|
| 27-60 | 22, 27, 32, 39, 43 | ARDLMEAGGMDV | IGHV3-53/3-66 | IGHJ6 | 19 |
| 35-08 | 35 | AREIGYSGSGSAKYFDP | IGHV1-69 | IGHJ5 | 1 |
| 35-15 | 35 | ARAEDHGTYYSDSSGYHFDY | IGHV1-69 | IGHJ4 | 1 |
| 35-46 | 35 | ARVHGYSGYGANDAFDI | IGHV1-69 | IGHJ3 | 2 |
| 35-68 | 35 | AREVGYSGFGASPKFDP | IGHV1-69 | IGHJ5 | 1 |
| 35-78 | 35 | AREPGILGYCSSTSCYID | IGHV1-69 | IGHJ4 | 1 |
| 43-09 | 43 | ARTGSGWTDAFDI | IGHV3-30 | IGHJ3 | 5 |
| 43-27 | 43 | ATTYHYDTDGPYGEFYY | IGHV5-51 | IGHJ4 | 1 |
| 43-34 | 43 | ARVRGYSGYGASGYFDN | IGHV1-69 | IGHJ4 | 1 |