TABLE 3.
Results of MTUS2 association with LOAD in independent cohorts.
| Cohort | SNP | bp (hg37) | N | B | SE | p | MAF | D' |
|---|---|---|---|---|---|---|---|---|
| NIA‐LOAD | rs775323299 | 28,795,404 | 4079 | 3.92 | 0.50 | 8.4 × 10−5 | 1.5 × 10−4 | NA |
| ABC‐DS | rs73164590 | 29,064,021 | 366 | 2.01 | 0.35 | 0.002 | 0.01 | 1.00 |
| omicsADDS | rs55646198 | 29,486,171 | 244 | 1.08 | 0.24 | 0.009 | 0.06 | 1.00 |
| ROSMAP | rs118034475 | 29,426,891 | 625 | 1.15 | 0.40 | 0.004 | 0.01 | 1.00 |
| WHICAP_NHW | rs68054178 | 29,128,208 | 839 | 4.12 | 0.62 | 3.7 × 10−5 | 0.07 | 1.00 |
| ADGC | rs581625 | 28,956,466 | 6977 | 3.15 | 0.60 | 0.002 | 0.17 | 0.42 |
Abbreviations: ABC‐DS, Alzheimer's Biomarkers Consortium‐Down Syndrome; ADGC, Alzheimer's Disease Genetic Consortium; LOAD, late‐onset Alzheimer's disease; NIA‐LOAD, The National Institute on Aging Alzheimer's Disease‐Late‐Onset Alzheimer's disease; omicsADDS, The Multiomic Studies of Alzheimer's Disease in Adults with Down Syndrome Study; ROSMAP, the Religious Orders Study/Memory and Aging Project; SNP, single nucleotide polymorphism; WHICAP, the Washington Heights/Inwood Columbia Aging Project.