TABLE 3.
Regional associations of POD with postoperative white matter alterations at follow‐up 3 months after surgery as indicated by interaction of JHU atlas region and POD.
| Metric | Region | Hemisphere | JHU atlas number | B ± SE | p |
|---|---|---|---|---|---|
| MD | Fornix | 6 | −0.000037 ± 0.000017 | 0.02850 | |
| Tapetum | L | 48 | − 0.000082 ± 0.000017 | <0.00001 | |
| FW | Tapetum | L | 48 | − 0.020 ± 0.007 | 0.00287 |
| FA | Sag. stratum | R | 31 | −0.013 ± 0.006 | 0.02489 |
| Sup. frontoocc. Fsc. | R | 43 | 0.015 ± 0.006 | 0.00932 | |
| MK | Medial lemniscus | L | 10 | −0.031 ± 0.014 | 0.03320 |
| Sup. frontoocc. Fsc. | L | 44 | −0.028 ± 0.014 | 0.04874 |
Note: Regions with more pronounced effects as estimated from the global association are highlighted in bold/italic. The table illustrates results for the 3 months follow‐up. The number of POD by region interactions was reduced using backward stepwise regression removing interactions using a significance criterion of p > 0.05. Please note that the corrected alpha‐level was p < 0.0042. The significant regions are in bold letters.