Table 5.
Source protein | Peptide sequence | Known restriction element | Copy level of peptide per cell | |
---|---|---|---|---|
VMM12 (HLA-A3) | VMM18 (HLA-A3) | |||
TAG | RLSNRLLLR | HLA-A3 | + [+]b | ++ [+] |
Unknown | SQNFPGSQK | HLA-A3 | ++ [?]c | ++ [?] |
TRP-2 | LLGPGRPYR | HLA-A31 | ++ [+] | NTd |
a+, One to ten copies per cell; ++, greater than ten copies per cell and equal to or less than 20 copies per cell
b[+] Indicates that the cell line was positive by PCR for the expression of the corresponding tumor antigen gene
c[?] Indicates that the tumor antigen is derived from an unknown source protein, and thus it is not possible to determine by PCR those cell lines expressing the corresponding tumor antigen gene
dNT not tested