Table 2.
BLCA-38 immunoreactivity in human prostate tumour biopsy samples: intensity of staining and percentage positivity. Intensity of staining was scored from + (weak) to ++ (moderate) to +++ (strong)
| Tissue | Number of biopsies | Frozen tissues | Number of biopsies | Formalin-fixed, paraffin-embedded tissues | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| − | + | ++ | +++ | ≥2+ | % | − | + | ++ | +++ | ≥2+ | % | |||
| Normal (in cancer tissue) | 7 | 6 | 1 | 0/7 | 0 | 13 | 8 | 5 | 0 | 0 | ||||
| Benign (BPH) | 2 | 2 | 0 | 0 | ||||||||||
| Benign (BPH, in cancer tissues) | 3 | 1 | 2 | 0/3 | 0 | 21 | 11 | 10 | 0/21 | 0 | ||||
| PIN | 2 | 1 | 1 | 0/2 | 0 | |||||||||
| PIN (in cancer tissues) | 3 | 2 | 1 | 1/3 | 33 | 21 | 11 | 6 | 3 | 1 | 4/21 | 21 | ||
| Cancer: Gleason score 6 | 6 | 1 | 1 | 4 | 4/6 | 67 | 22 | 3 | 5 | 14 | 14/22 | 64 | ||
| Gleason score 7 | 13 | 4 | 6 | 10/13 | 77 | 7 | 3 | 4 | 4/7 | 57 | ||||
| Gleason score 8 | 3 | 2 | 2/3 | 67 | ||||||||||
| Gleason score 9 | 4 | 3 | 2 | 2 | 4/4 | 100 | 1 | 1 | 1/1 | 100 | ||||
| Overall BLCA-38 reactivity | 18/23 | 78 | 21/33 | 64 | ||||||||||