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Cytotoxic activity of splenocytes against B16 melanoma cells. Spleen cells were derived from mice in the combined therapy group (treated with rmHSP70 (80 μg) injection plus hyperthermia treatment) at 14 days after hyperthermia treatment (open circles) and naive mice (solid circles). Effector cell to target cell (E:T) ratios ranged from 3.125 to 25:1. Data points and bars represent mean and SD of three independent experiments
