Fig. 5.

Inhibition of protein synthesis by serum of αCD86-IT–treated rhesus monkeys. Sera from rhesus monkeys taken at the indicated times were added to L540 cells for 72 h and additional 16 h with ³H-leucine. Inhibition of protein synthesis is expressed as percentage of ³H-leucine incorporation by untreated cells. a Sera from all monkeys were analyzed at dilutions 1:50 (Fig. 4a). b From the two monkeys treated with 0.1-mg/kg αCD86-IT, sera were also analyzed at 1:10 (Fig. 4b)