Fig. 2a–c.

Induction of apoptosis of F9 cells by Id-specific Th1 cells is inhibited by anti-FasL mAb. [³H]TdR-labeled F9 target cells were incubated with cloned Id-specific Th1 7A10B2 cells (a), or day 10 Th1-polarized (b), or Th2 polarized (c) cells from Id-specific TCR-transgenic mice in the presence of anti-FasL mAb MFL1 (solid squares) or control hamster mAb UC8 (open squares) or medium (gray column). In c, only the highest mAb concentration (50 μg/ml) was tested. E/T ratio was 10:1 in all experiments