TABLE 2.
Plaquing efficiency of ICP10ΔPK virus in dividing and serum-starved cells
| Virus | Cells (serum concn [%])a | Virus titerb (wild-type/mutant ratio) |
|---|---|---|
| HSV-2 | Vero (10) | 5.0 × 107 |
| ICP10ΔPK | Vero (10) | 2.8 × 107 (1.8) |
| HSV-2 | Vero (0.5) | 4.7 × 107 |
| ICP10ΔPK | Vero (0.5) | 3.5 × 104 (1.3 × 103) |
| HSV-2 | Vero-ICP10 (10) | 4.9 × 107 |
| ICP10ΔPK | Vero-ICP10 (10) | 2.2 × 107 (2.2) |
| HSV-2 | Vero-ICP10 (0.5) | 4.6 × 107 |
| ICP10ΔPK | Vero-ICP10 (0.5) | 2.0 × 107 (2.3) |
a
Plaque assays were done in medium containing 10 or 0.5% serum.
b
In PFU per milliliter.