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. 2024 Mar 27;27(5):109600. doi: 10.1016/j.isci.2024.109600

Figure 3.

Figure 3

Primary HBCs activated in vitro enhance Rac1-mediated signaling

(A) Representative western blots depicting p63, Rac1, pcJun, total cJun, and GAPDH abundances in cultures of vehicle-treated (PMA-/EHT1864-), activated (PMA+/EHT1864-), activated and Rac1 inhibited (PMA+/EHT1864-), and Rac1 inhibited (PMA-/EHT1864+) HBCs.

(B–D) Quantification of densitometric measurements for p63 (B), Rac1 (C), and normalized pcJun per normalized total cJun (D) abundances (n = 3 independent trials), vehicle-treated used as baseline, error bars indicate mean +SEM, one-way ANOVA with post hoc Tukey’s multiple comparisons test, ∗<0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.