Table 1.
Descriptives: children with sex chromosome trisomy versus controls.
| SCT | XXX | XXY | XYY | Control | XX | XY | p d | SCT comparisonse | |
|---|---|---|---|---|---|---|---|---|---|
| Total N | 72 | 27 | 29 | 16 | 71 | 40 | 31 | ||
| Age—Mean (SD) | 4.80 (1.29) | 4.89 (1.19) | 4.61 (1.35) | 4.98 (1.40) | 4.51 (.99) | 4.53 (1.08) | 4.49 (.90) | .138 | n.s. |
| Global intellectual functioningaRange | 95.19 (19.37) 55–138 | 92.85 (16.88) 60–122 | 99.59 (20.11) 55–138 | 91.07 (21.89) 59–125 | 108.31 (13.80) 72–140 | 106.50 (12.81) 76–137 | 110.65 (14.86) 72–40 | <.001 | n.s. |
| Socio-economic statusb | 5.90 (.96) | 5.94 (.93) | 5.98 (.95) | 5.66 (1.03) | 5.42 (1.45) | 5.21 (1.37) | 5.68 (1.52) | .021 | n.s. |
| Time of Diagnosis (prenatal/postnatal) | 40/32 | 15/12 | 16/13 | 9/7 | n.s. | ||||
| Ascertainment bias (A/B/C)c | 31/21/20 | 7/10/10 | 15/8/6 | 9/3/4 | n.s. |
Note: Scores represent Means (SD).
Abbreviations: n.s. = not significant; SCT = Sex Chromosome Trisomy.
Measured with the WPPSI-III or the Wechsler Nonverbal Scale of Ability; Data for 5 children with SCT was incomplete (1 XXX, 2 XXY, 2 XYY).
Classified according to the criteria of Hollingshead: 0) No formal education; 1) Less than 7th grade; 2) Junior high school; 3) Partial high school; 4) High school graduate; 5) Partial college or specialized training; 6) Standard college/university graduation; 7) Graduate/professional training.
A = Active prospective follow-up, B = Information seeking parents, C = Clinically referred.
p-value SCT versus Control comparison.
SCT comparisons: XXX versus XXY versus XYY.