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. Author manuscript; available in PMC: 2025 Mar 1.
Published in final edited form as: Appetite. 2023 Dec 2;194:107150. doi: 10.1016/j.appet.2023.107150

Figure 2.

Figure 2.

Early-adolescent (WD-EA) vs. late-adolescent (WD-LA) consumption of a cafeteria-style Western diet (WD) does not significantly alter body weight trajectories or body composition in male or female rats. (A) Body weight over time for male rats, with periods of exposure to the WD diet indicated within the dotted vertical lines (two-way ANOVA with diet, time [as repeated measure], and a diet × time interaction as factors; for diet, P=0.9147; for time, P<0.0001; for diet × time interaction, P=0.9990). (B) Body composition for male rats at PN 78 after the shorter healthy diet intervention period (one-way ANOVA with diet as the factor; % fat, P=0.3680; fat-to-lean ratio, P=0.3576; % lean, P=0.3351). (C) Body weight over time for female rats, with periods of exposure to the WD diet indicated within the dotted vertical lines (Mixed effects model with factors of diet [fixed], time [fixed, as repeated measure], diet × time interaction [fixed], subject [random]; for diet, P=0.9999; for time, P<0.0001; for diet × time interaction, P=0.8673). (D) Body composition for female rats at PN 78 after the shorter healthy diet intervention period (one-way ANOVA with diet as the factor; % fat, P=0.4590; fat-to-lean ratio, P=0.8414; % lean, P=0.3947). Error bars represent ± standard error of the mean; n=11–13/group. ANOVA, analysis of variance; WD, cafeteria diet; WD-EA, early-adolescent WD diet exposure; WD-LA, late-adolescent WD diet exposure; PN, postnatal day.