Scheme 1.

Sequence of conversions that represent a linear model of the transformation of normal fibroblasts (nF) to myofibroblasts (mF). The nF are supplied from precursors (r0) and the mF are subject to apoptosis (k3).

$$r_0\stackrel{k_0}{\to }nF\underset{k_{-1}}{\overset{k_1}{\rightleftharpoons }}pmF\underset{k_{-2}}{\overset{k_2}{\rightleftharpoons }}mF\stackrel{k_3}{\to }\varnothing$$