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. 2023 Aug 17;21(4):312–330. doi: 10.20892/j.issn.2095-3941.2023.0129

Table 2.

Research on network-based methods for resolving multi-omics data

Method category Modeling methods Input Application Refs
Multi-layer integration Dimensionality reduction Multi-layer network Multi-layer clustering 52
Multi-layer integration Similarity measurement Multi-layer network Multi-layer clustering 57
Multi-layer integration Network structure analysis Multi-layer network Multi-level biological network construction and resolution 59
Multi-layer integration Network structure analysis and machine learning Multi-layer network Multi-level biological network construction and disease gene prediction 61
Dynamic feature identification Representation learning Dynamic network Network topology dynamic representation 63
Dynamic feature identification Dynamic embedding Dynamic network Dynamic features identification and anomaly detection 65
Dynamic feature identification State transition simulation Dynamic biological network Dynamic features identification, early warning signals 66
Dynamic feature identification Multiscale modeling Dynamic biological data Simulation of tumorigenesis 67