Table 1.
Intervention | Class of Recommendation | Level of Evidence | ||
---|---|---|---|---|
Pre-Operative | ||||
Pre-Habilitation | IIa (Moderate) | B – Non-Randomized | ||
Carbohydrate Loading Avoidance of Prolonged Fasting | IIb (Weak) | C – Limited Data | ||
Correction of Nutritional Deficiency and Support | IIa (Moderate) | C – Limited Data | ||
Pre-operative Smoking and Alcohol Cessation | I (Strong) | C – Limited Data | ||
Patient Engagement and Access to Technology | IIa (Moderate) | C – Limited Data | ||
Intra-Operative | ||||
Anti-Fibrinolytics | I (Strong) | A | ||
Avoidance of Hyperthermia | III: Harm (Strong) | B – Non-Randomized | ||
Infection Reduction Bundle | I (Strong) | B – Non-Randomized | ||
Optimization of Sternal Closure | IIa (Moderate) | B – Non-Randomized | ||
Post-Operative | ||||
Early Extubation | IIa (Moderate) | B – Non-Randomized | ||
Multimodal Analgesia | I (Strong) | B – Non-Randomized | ||
Delirium Screening | I (Strong) | B – Non-Randomized | ||
Goal-Directed Therapy | I (Strong) | B – Randomized | ||
Chemical Thromboprophylaxis | IIa (Moderate) | C – Limited Data | ||
Perioperative Glycemic Control | I (Strong) | B – Randomized | ||
Avoidance of Hypothermia | I (Strong) | B – Non-Randomized | ||
Avoidance of Acute Kidney Injury and Biomarkers for Early Detection | IIa (Moderate) | B – Randomized | ||
Chest Tube Drain Management | I (Strong) | B – Randomized |