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Average peak calcium transient measures following the coapplication of 3 mM choline and 1 μM PNU120596 in cells transfected with variants of the α7 receptor
Cells were pretreated with Ry (30 μM) or Xest. C (1 μM).
| Receptor | Vehicle (ΔF/Fθ) | Ry (ΔF/Fθ) | Xest. C (ΔF/Fθ) |
|---|---|---|---|
| α7endogenous | 4858.25% ± 468.65% | 1398.76% ± 382.33% | 1583.34% ± 240.76% |
| α7D44A | 2654.13% ± 498.24% | 1115.99% ± 234.19% | 1696.25% ± 259.46% |
| α7345–348A | 3322.11% ± 474.83% | 1965.54% ± 282.33% | 2647.60% ± 432.65% |
