Table 2.
Adverse events based on a questionnaire
| Any (score of 1, 2, or 3) | VAM triple therapy | VAC triple therapy | P |
|---|---|---|---|
| Diarrhea | 33% | 37% | 0.82 |
| Dysgeusia | 21% | 17% | 1 |
| Nausea | 14% | 2% | 0.11 |
| Anorexia | 23% | 5% | 0.03 |
| Abdominal pain | 23% | 23% | 1 |
| Heartburn | 16% | 12% | 0.76 |
| Hives | 0% | 5% | 0.49 |
| Headache | 16% | 16% | 1 |
| Abdominal fullness | 56% | 14% | <0.001 |
| Belching | 21% | 12% | 0.38 |
| Vomiting | 0% | 0% | 1 |
| General malaise | 16% | 9% | 0.52 |
| Other | 2% | 5% | 1 |
| Any (score of 2 or 3) | |||
| Diarrhea | 16% | 7% | 0.31 |
| Dysgeusia | 21% | 12% | 0.38 |
| Nausea | 7% | 0% | 0.24 |
| Anorexia | 9% | 0% | 0.12 |
| Abdominal pain | 7% | 2% | 0.62 |
| Heartburn | 5% | 2% | 1 |
| Hives | 0% | 2% | 1 |
| Headache | 5% | 2% | 1 |
| Abdominal fullness | 28% | 2% | 0.007 |
| Belching | 9% | 2% | 0.36 |
| Vomiting | 0% | 0% | 1 |
| General malaise | 2% | 0% | 1 |
| Other | 0% | 0% | 1 |
| Score of 3 | |||
| Diarrhea | 5% | 5% | 1 |
| Dysgeusia | 2% | 9% | 0.36 |
| Nausea | 0% | 0% | 1 |
| Anorexia | 2% | 0% | 1 |
| Abdominal pain | 2% | 0% | 1 |
| Heartburn | 0% | 0% | 1 |
| Hives | 0% | 2% | 1 |
| Headache | 2% | 2% | 1 |
| Abdominal fullness | 7% | 2% | 0.62 |
| Belching | 0% | 0% | 1 |
| Vomiting | 0% | 0% | 1 |
| General malaise | 0% | 0% | 1 |
| Other | 0% | 0% | 1 |
VAC triple therapy, vonoprazan + amoxicillin + clarithromycin 1‐week eradication therapy; VAM triple therapy: vonoprazan + amoxicillin + metronidazole 1‐week eradication therapy. The bold showes less than 0.05.