Table 2.

T-cell precursor frequencies of donors with different human leukocyte antigen (HLA)-DR genotypes

Peptide	Donor	HLA-DR	Positive wells/total wells	Estimated frequency
CEA116	BCM-02	DR01/04	4/48	0.08–0.33×10−6
	BCM-04	DR13/14	3/48
	BCM-19	DR04/15	3/48
	BCM-28	DR11/13	1/48
	BCM-36	DR04/04	3/48
	BCM-40	DR04/13	2/48
	BCM-44	DR01/15	4/48
CEA176	BCM-26	DR04/08	26/48	0.33–2.41×10−6
	BCM-39	DR04/14	4/48
	BCM-40	DR04/13	29/48
CEA588	BCM-02	DR01/04	3/48	0–1.17×10−6
	BCM-04	DR13/14	5/48
	BCM-19	DR04/15	0/48
	BCM-26	DR04/08	14/48
	BCM-28	DR11/13	2/48
	BCM-36	DR04/04	3/48
	BCM-39	DR04/14	0/48
CEA624	BCM-02	DR01/04	5/48	0–1.08×10−6
	BCM-04	DR13/14	4/48
	BCM-19	DR04/15	0/48
	BCM-26	DR04/08	13/48
	BCM-28	DR11/13	1/48
	BCM-36	DR04/04	3/48
	BCM-39	DR04/14	1/48
CEA665	BCM-04	DR13/14	4/48	0–0.33×10−6
	BCM-19	DR04/15	0/48
	BCM-28	DR11/13	3/48
	BCM-36	DR04/04	3/48
	BCM-39	DR04/14	0/48
	BCM-40	DR04/13	4/48
	BCM-44	DR01/15	4/48