Skip to main content
. 2004 Dec 22;54(8):799–806. doi: 10.1007/s00262-004-0643-4

Table 2.

Histopathological findings of cynomolgus monkeys treated with DT388IL3 intravenously for up to six every other day doses

Histopathological findings 100 ug/kg dose group 150 ug/kg dose group
#7228 #7229 #7225 #7226 #7227
Hepatocellular swelling 1 1 1 1
Extramedullary hematopoeisis 1 1 1 2
Myeloid hyperplasia 1 1 2 3
Lymphoplasmacytic gastritis or colitis 1 1 1
Lymphoid depletion, spleen 1 1
Lymphoid follicular hyperplasia 2 2

1 mild, 2 moderate, 3 marked, 4 severe

HHS Vulnerability Disclosure