Fig. 8.

Comparison of total metastatic area between treatment and control groups in C57B1/6 mice. Comparison of total area of metastases between groups demonstrated a significantly greater reduction in tumor area in the Albuleukin treatment group than observed in the rIL-2 group. Both rIL-2 and Albuleukin reduced the area of tumor involvement when compared to the placebo and HSA controls (p<0.05). Each point reflects the total tumor area on the liver surface for a single mouse. The group means are shown with a bar, n=12 mice per group. Statistical differences in tumor area were evaluated by an unpaired t test. Values of p<0.05 were considered statistically significant