Fig. 6.

Blockade of PD-L inhibits IFN-γ’s tumor-promoting effect. Mice (n=8 per group) were inoculated with 8×10³ (left) or 5×10⁴ (right) H22 tumor cells and treated with saline, 10 μg of mIFNG plasmid and 100 μg of pcDNA3.1 or pPD-1A plasmid for eight times. Tumor incidence by day 40 after inoculation (a) and mean tumor weight (MTW) by day 20 after inoculation (b) are shown. Data are representative of two experiments