Fig. 1.

Cross-study validation of data generated by Quaglino et al. [26] and De Giovanni et al. [8; Astolfi, unpublished results] reveals significant agreement of the gene expression patterns in these two independent studies. Cross-experiment consistency of expression patterns was evaluated with an integrative correlation (IC) coefficient that quantifies cross-study reproducibility without relying on direct assimilation of expression measurements across experiments. a Histogram of the empirical distribution of the gene-specific correlation of correlations. b Scatterplot of the pairwise correlation comparison within the probe sets in the two datasets.