Table 1.
Probe sets found differentially expressed in vaccinated as opposed to untreated mice
| Probe Set IDab | Cluster in Fig. 5 | Chromosomal location | Locus link | Description | Function |
|---|---|---|---|---|---|
| 160353_i_at | c | 1 E4 | 17164 | MAP kinase-activated protein kinase 2 | Signal transduction |
| 102906_at | b | 11 B1.2 | 21822 | T-cell specific GTPase | Signal transduction |
| 98349_at | c | 13 D2.2 | 16195 | Interleukin 6 signal transducer | Signal transduction |
| 104750_at | d | 11 B1.2 | 18356 | Interferon gamma hitinos protein | Signal transduction |
| 160933_at | d | 11 32.0 cM | 16145 | Interferon gamma induced GTPase | Signal transduction |
| 97409_at | d | 11 B1.2 | 15944 | Interferon protein 1 | Signal transduction |
| 102259_at | c | 5 75.0 cM | 22628 | 3-Monooxgenase/tryptophan 5-monooxgenase activation protein | Signal transduction |
| 97227_at | c | 5 82.0 cM | 14673 | Guanine nucleotide binding protein, alpha 12 | Signal transduction |
| 101465_at | d | 1 25.9 cM | 20846 | Signal transducer, activator of transcription 1 | Signal transduction |
| 100368_at | c | 4 E1 | 12371 | Caspase 9 | Apoptosis |
| 101845_s_at | d | 1 53.1 cM | 114564 | Kappa light chain variable region mRNA | Immunoglobulin |
| 100362_f_at | e | – | – | Ig V(H)II gene H8 | Immunoglobulin |
| 100376_f_at | e | – | – | Heavy chain variable region precursor gene | Immunoglobulin |
| 100583_at | e | 12 59.0 cM | 16061 | IgH chain gene | Immunoglobulin |
| 101718_f_at | e | – | 213684 | Similar to Ig light chain variable region | Immunoglobulin |
| 101743_f_at | e | 12 59.0 cM | 16061 | Ig heavy chain (J558 family) | Immunoglobulin |
| 101870_at | e | 12 58.0 cM | 16017 | Ig heavy chain 4 (serum IgG1) | Immunoglobulin |
| 101871_f_at | e | 12 F1 | 382657 | Similar to anti-human CD19 moAb 4G7 Ig gamma1 heavy chain | Immunoglobulin |
| 102372_at | e | 5 E1 | 16069 | Ig joining chain | Immunoglobulin |
| 102823_at | e | 12 F1 | 380794 | Similar to Ig gamma-2b chain membrane | Immunoglobulin |
| 102824_g_at | e | 12 F1 | 380794 | Similar to Ig gamma-2b chain membrane | Immunoglobulin |
| 102843_s_at | e | 12 58.0 cM | 16014 | Ig heavy chain 4 (serum IgG1) | Immunoglobulin |
| 93638_s_at | e | 16 13.0 cM | 16142 | Ig lambda chain, variable 1 | Immunoglobulin |
| 93904_f_at | e | – | – | Ig heavy chain VDJ region gene | Immunoglobulin |
| 93927_f_at | e | 12 59.0 cM | 16061 | Ig heavy chain 4 (serum IgG1) | Immunoglobulin |
| 97008_f_at | e | – | – | Ig variable region heavy chain precursor | Immunoglobulin |
| 97563_f_at | e | 12 | – | Ig heavy chain 1 (serum IgG2a) | Immunoglobulin |
| 97574_f_at | e | – | – | Ig heavy chain variable region precursor | Immunoglobulin |
| 97575_f_at | e | – | – | Ig heavy chain variable region precursor | Immunoglobulin |
| 97576_f_at | e | 12 | – | Ig heavy chain 4 | Immunoglobulin |
| 98765_f_at | e | – | – | Ig heavy chain V region mRNA | Immunoglobulin |
| 99420_at | e | 12 59.0 cM | 16059 | Ig heavy chain (V7183 family) | Immunoglobulin |
| 102904_at | b | 17 18.7 cM | 14968 | Histocompatibility 2, class II antigen E alpha | Immune response |
| 94285_at | d | 17 18.66 cM | 14969 | Histocompatibility 2, class II antigen E beta | Immune response |
| 103202_at | d | 3 H1 | 55932 | Guanylate nucleotide binding protein 3 | Immune response |
| 104597_at | d | 3 67.4 cM | 14469 | Guanylate nucleotide binding protein 2 | Immune response |
| 95974_at | d | 3 67.4 cM | 14468 | Guanylate nucleotide binding protein 1 | Immune response |
| 161968_f_at | b | 9 | – | Chemokine (C-C motif) receptor 5 | Inflammatory response |
| 92459_at | b | 11 47.0 cM | 20307 | Chemokine (C-C motif) ligand 8 | Inflammatory response |
| 101436_at | d | 5 53.0 cM | 17329 | Chemokine (C-X-C motif) ligand 9 | Inflammatory response |
| 102719_f_at | d | 9 72.0 cM | 12774 | Chemokine (C-C motif) receptor 5 | Inflammatory response |
| 101028_i_at | c | 2 64.0 cM | 11464 | Actin, alpha | Structural molecule activity |
| 101080_at | c | 2 18.0 cM | 12831 | Procollagen, type V, alpha 1 | Structural molecule activity |
| 101095_at | c | 4 D3-E1 | 17150 | Microfibrillar-associated protein 2 | Structural molecule activity |
| 102990_at | c | 1 21.1 cM | 12825 | Procollagen, type III, alpha 1 | Structural molecule activity |
| 103709_at | c | 11 56.0 cM | 12842 | Procollagen, type I, alpha 1 | Structural molecule activity |
| 92207_at | c | 5 75.0 cM | 13717 | Elastin | Structural molecule activity |
| 92836_at | c | 5 75.0 cM | 13717 | Elastin | Structural molecule activity |
| 93517_at | c | 10 41.1 cM | 12834 | Procollagen, type VI, alpha 2 | Structural molecule activity |
| 94305_at | c | 11 56.0 cM | 12842 | Procollagen, type I, alpha 1 | Structural molecule activity |
| 99367_at | c | 2 H1 | 13589 | Microtubule-associated protein, RP/EB family, member 1 | Structural molecule activity |
| 92559_at | d | 3 50.8 cM | 22329 | Vascular cell adhesion hitinos 1 | Structural molecule activity |
| 100463_at | a | 5 44.93 cM | 12993 | Casein gamma | Transport |
| 96030_at | a | 5 44.9 cM | 12990 | Casein alpha | Transport |
| 99130_at | a | 5 44.91 cM | 12991 | Casein beta | Transport |
| 102704_at | c | 18 6.0 cM | 11829 | Aquaporin 4 | Transport |
| 102708_at | a | 13 12.0 cM | 12231 | Butyrophilin, subfamily 1, member A1 | Transport |
| 160949_at | c | 14 B | 26430 | Poly (ADP-ribose) glycohydrolase | DNA damage responses |
| 92833_at | b | 10 51.0 cM | 15109 | Histidine ammonia lyase | Biosynthesis |
| 160617_at | c | 7 B5 | 50794 | Kruppel-like factor 13 | Transcription |
| 103926_at | c | 16 A1 | 208643 | Ribosomal protein L24 | Translation |
| 101139_r_at | c | 5 E1 | 17830 | Mucin 10 | Biological-process unknown |
| 102860_at | d | 12 E | 20715 | Serine (or cysteine) proteinase inhibitor, clade A, member 3G | Biological-process unknown |
| 93085_at | d | 17 18.59 cM | 16912 | Proteosome subunit, beta type 9 (large multifunctional protease 2) | Biological-process unknown |
| 102931_at | a | 11 0.5 cM | 22373 | Whey acidic protein (WAP) | Biological-process unknown |
| 93028_at | c | 7 69.03 cM | 14955 | H19 fetal liver mRNA | Biological-process unknown |
| 103033_at | b | 17 18.83 cM | 20567 | Sex-limited protein | Biological-process unknown |
| 99126_at | c | X | – | Inactive X specific transcripts | Biological-process unknown |
| 99850_at | b | 15 | – | RIKEN cDNA 4432409D24 gene | Biological-process unknown |
| 101518_at | c | 11 B5 | 55978 | RIKEN cDNA 0610009H04 gene | Biological-process unknown |
| 103905_at | c | 9 C | 76459 | RIKEN cDNA 2310047E01 gene | Biological-process unknown |
| 100944_at | b | 19 | – | Expressed sequenze AW112010 | Biological-process unknown |
| 103963_f_at | d | 18 E1 | 60440 | Expressed sequenze AW111922 | Biological-process unknown |
| 96764_at | d | 18 E1 | 60440 | Expressed sequence AW111922 | Biological-process unknown |
| 98410_at | d | 11 B1.3 | 54396 | Expressed sequenze AI481100 | Biological-process unknown |
| 102721_at | e | 12 F1 | 380795 | EST | Biological-process unknown |
| 102722_g_at | e | 12 F1 | 380795 | EST | Biological-process unknown |
| 160173_at | c | – | – | EST (acc: AI852838) | Biological-process unknown |
| 100880_at | d | – | – | EST (acc: AA816121) | Biological-process unknown |
aExpression data related to the present probe sets can be requested to the authors
b34/37 probe sets found over-represented in chromosome 6 were linked to Ig k light chain genes: 21 probe sets were linked to variable region (V) 28, 3 to V8, 1 to V1, 1 to V20, 1 to V21, and the others were simply annotated as Ig k genes. Probe sets are grouped on the basis of their putative function. Functional groups were inferred by probesets Gene Ontology (http://www.geneontology.org) annotation or by GeneRIF (http://www.ncbi.nih.gov/entrez/query.fcgi?db=gene) annotation