Fig. 3.

CD8⁺ T cells infiltrating the MUC1 DTH site are IFN-γ producers. MUC1 peptide and hepatitis B antigen were injected intradermally 14 days after the last injection, and injection sites biopsied 48 h later. One third of the biopsy sample was minced and cultured for 48 h to allow infiltrating T cells to exit the skin fragments. The cells were analyzed by flow cytometry. The example shown is from the 100-μg dose peptide group.