Table 1.
Participant | Age | Sex | Race | Diagnosis | Vaccine type | Mycophenolate Dose | Number of doses held | Concurrent Therapy | Antibody Titer * | Flare |
---|---|---|---|---|---|---|---|---|---|---|
1 | 36 | M | White | CT-ILD† | Moderna | 2000mg | 3 | No | >250 | No |
2 | 62 | F | White | CT-ILD† | Pfizer | 500mg | 88 | Prednisone | >250 | No |
3 | 19 | F | White | IA‡ | Pfizer | 1000mg | 5 | Abatacept | 16 | Yes |
4 | 58 | F | White | IA‡ | Pfizer | 2000mg | 28 | Tofacitinib | >250 | No |
5 | 46 | F | White | Myositis | J+J | 2000mg | NA | Prednisone | 82 | No |
6 | 53 | F | White | Myositis | J+J | 2500mg | 56 | Prednisone | 206 | No |
7 | 46 | F | White | Myositis | Pfizer | 3000mg | 20 | IVIG§, HCQ|| | 40 | No |
8 | 54 | F | White | Myositis | Pfizer | 3000mg | NA | No | <0.40 | No |
9 | 35 | F | White | Myositis | Moderna | 3000mg | 24 | No | >250 | No |
10 | 71 | F | White | Overlap CTD¶ | Moderna | 2000mg | 4 | Rituximab | 9.0 | No |
11 | 58 | F | White | Overlap CTD¶ | Moderna | 2000mg | 9 | HCQ||, Prednisone | 8 | No |
12 | 55 | F | White | Overlap CTD¶ | Moderna | 2000mg | 30 | HCQ||, Prednisone | 8 | No |
13 | 64 | F | White | Overlap CTD¶ | Pfizer | 500mg | 38 | No | >250 | No |
14 | 70 | M | White | Scleroderma | Moderna | 3000mg | 42 | Rituximab | <0.40 | Yes |
15 | 36 | F | White | Scleroderma | Pfizer | 3000mg | 14 | No | 35 | No |
16 | 40 | F | White | Scleroderma | Pfizer | 2500mg | 28 | No | 244 | No |
17 | 42 | F | White | Scleroderma | Pfizer | 3000mg | 8 | Abatacept | 22 | No |
18 | 63 | F | White | Sjogren’s | Pfizer | 2500mg | NA | No | 12 | No |
19 | 49 | F | White | SLE | J+J | 3000mg | 13 | No | >250 | No |
20 | 54 | F | White | SLE | Moderna | 1000mg | 10 | HCQ‡ | >250 | No |
21 | 50 | F | Black | SLE | Pfizer | 3000mg | 98 | Belimumab, Prednisone | >250 | No |
22 | 31 | F | White | SLE | Pfizer | 2000mg | 10 | HCQ‡, Prednisone | 80 | No |
23 | 38 | F | White | SLE | Pfizer | 1500mg | 20 | Prednisone | 168 | No |
24 | 51 | F | White | SLE | Moderna | 1000mg | 5 | Abatacept | >250 | No |
The assay ranges from <0.4 to >250 units/mL. Positive antibody was defined as an anti-SARS-CoV-2 RBD antibody titer >0.79 units/mL
Denotes connective tissue disease related ILD
Rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, reactive arthritis, or inflammatory bowel disease associated arthritis
Intravenous Immunoglobulin
Hydroxychloroquine
Denotes a combination of two or more of the rheumatic conditions