Fig. 7.

Tongue megakaryocytes differ from bone marrow megakaryocytes. (A) Quantification of flow cytometry data showing percentage of megakaryocytes (CD41+ cells) that are also positive for CD34 in sham or infected tongue and bone marrow on Day 2 using gating strategy in Supplementary Figure 3. N = 3 mice per cohort, analyzed by one-way ANOVA. Mean ± SEM. (B) Quantification of mean fluorescent intensity of CCR7, MHCII, and CD86 expression on tongue and bone marrow megakaryocytes. N = 3 mice per cohort, analyzed by Student’s t test. Mean ± SEM. **p < 0.01, ***p < 0.001, n.s. is not significant. ANOVA = analysis of variance; CCR7 = C-C chemokine receptor type 7; CD = cluster of differentiation; MHCII = major histocompatibility complex class II; SEM = standard error of the mean.