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. Author manuscript; available in PMC: 2024 Apr 22.
Published in final edited form as: Mucosal Immunol. 2024 Jan 6;17(2):155–168. doi: 10.1016/j.mucimm.2024.01.001

Fig. 9.

Fig. 9

M.tb-infected ATs in early infection in the mouse model. (A) Extended ortho-section and (B) 3D view of M.tb bacilli intracellular in AT cells in the lungs of C57BL/6 mice infected with M.tb Erdman constitutively expressing Td-Tomato (orange) at 15 days post-infection. Podoplanin, PDPN (positive type I ATs, green); CD45 (leukocyte marker, pink), and DAPI (DNA/ nuclei marker, blue in panel A only). <scalebars (A) 15 μm, (B) 5 μm>. 3D = three-dimensional; ATs = alveolar epithelial type cells; DAPI = 4’,6-diamidino-2-phenylindole; DNA = deoxyribonucleic acid; M.tb = Mycobacterium tuberculosis; PDPN = podoplanin.