Fig. 4.
Standard dose rate (SDR) versus ultrahigh dose rate (uHDR) effects on inflammatory response. (A) Representative images (magnification 20 ×) of microglia/macrophages CD68− positive cells at 7 days post-irradiation of mouse brain cortex. Arrowheads indicate CD68-positive cells. (B) Quantification of CD68+ cells per analyzed area (~500 × 500 μm2) at 7 days. Bars represent means with standard error of the means (SEM) (Ctrl = 5, SDR = 5, uHDR = 5 brains, 10 regions of interest per tissue section were analyzed). Treatments were compared using ANOVA Tukey’s post hoc test, SEM (***P < .005).