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. 2024 Apr 1;5(1):iqae003. doi: 10.1093/oxfimm/iqae003

Figure 1.

Figure 1.

Activation marker expression on the innate immune cells and the T cell compartment after SGE treatment. Cells were exposed to SGE for 48 h. (a) Increased proportion of macrophages (CD45+ CD11b+CD14+) expressing CCR2 after being treated with SGE from Ae. aegypti WT. (b) Increased proportions of neutrophils (CD45+ CD15+CD16+) expressing CD69 after being treated with SGE from Ae. aegypti USDA and WT strains. (c and d) No significant change in the expression of activation markers CD25 and HLA-DR on CD4+ T cells. (e and f) No significant difference in the expression of activation markers PD-1 and HLA-DR on CD8+ T cells. Statistical analysis were performed with Wilcoxon signed-rank test two tailed comparing the unstimulated condition to each of the different stimulated conditions. Bars indicate median and interquartile range. Gray: unstimulated condition, Red: SGE from Ae. aegypti USDA strain, Yellow: SGE from Ae. aegypti WT strain, Green: SGE from Ae. albopictus WT strain. N = 8 individuals. *P < 0.05.