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. 2024 Apr 23;25:161. doi: 10.1186/s12859-024-05768-9

Table 6.

Wall clock time (s) and maximum RAM usage (GB) for algorithms on assigning simulated long reads (LR)

Algorithm LR to REF-1 LR to REF-2
Time (s) RAM (GB) Time (s) RAM (GB)
Mora 56.32 0.77 98.72 2.04
AugPatho2 341.93 21.52 429.23 22.522
Minimap2 1074.89 11.228 8696.29 20.048
Kraken2 193.08 2.58 326.09 25.01
Clark* 56.68 40.80 51.31 36.65

Mora used significantly fewer resources than AugPatho2 and was substantially faster. Time and RAM cannot be directly compared between the Mora/AugPatho2 and Kraken/Clark as Mora and AugPatho2 requires Minimap2 to give them an output file. Clark has an asterisk to signify that had errors in building the REF-2 database, which resulted in less resources used. All algorithms were run with 8 threads on a Google cloud virtual machine instance of type c2-standard-60